CLINICAL FEATURES OF CKD5D PATIENTS AND SYMPTOMATIC INTRADIALYSIS HYPOTENSION
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Keywords

hemodialysis, chronic kidney disease, intradialytic hypotension, levocarnitine , midodrine , food deprivation.

Abstract

The study included 82 patients with CKD5d, the inclusion criterion was the presence of a risk of developing symptomatic intradialytic hypotension according to the Rice scale of SIH developed by our group. This sample of patients was randomly divided into 3 comparison groups: food deprivation, levocarnitine infusion, and midodrine administration immediately before the hemodialysis session. The study compared the groups by the incidence of SIH and other complications of the procedure. In patients with CKD5d at risk of SIH, the use of midodrine before HD can reduce the severity of the decrease in blood pressure and reliably prevent the development of SIH in 39% of patients. Food deprivation and a single levocarnitine infusion did not have a significant effect on the dynamics of SBP and the incidence of SIH.
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