Abstract
Parvovirus B19 is a common and highly contagious infectious disease, and the
disease due to facial rash is referred to in some literatures as "infectious erythema", "the
fifth disease". In children, the disease is mild and often does not require treatment. In
patients with hemolytic pathology (hereditary spherocytosis, sickle cell anemia),
immunodeficiency (congenital immunodeficiency), receiving immunosuppressive therapy,
in HIV infection Parvovirus B19 causes aplastic crisis due to high erythrocyte aplasia,
chronic aplastic crisis. B19 infection is considered dangerous for patients with hemolytic
pathology.