Abstract
The results of the aggregation data in 122 patients with multivessel coronary lesions,
including 67 men, 55 women (mean age 61.83 ± 19.5 years), were analyzed in this study. The
patients are divided into 2 groups depending on the presence of diabetes mellitus. Thus, the study
of the features of antiplatelet therapy in patients with diabetes mellitus demonstrated a
significantly pronounced ADP-induced rate and degree of platelet aggregation in comparison with
the group of patients without diabetes mellitus. The group of patients with diabetes and unstable
forms of coronary artery disease had significantly higher rates of spontaneous and adrenalineinduced platelet aggregation rate than the group of patients with stable coronary artery disease.
A relationship was found between glycated hemoglobin levels above 7% and the rate of
spontaneous and collagen-induced platelet aggregations.