Abstract
This study assessed protective role of Virgin Coconut Oil (VCO) following
atrazine- induced glucose metabolic derangement in rats. Adult male albino wistar rats
weighing 180-200 g body weight were used for the study. They were randomly separated
into two major experimental groups (The test and recovery groups). Treatment in the test
group lasted for 2 weeks, after which the animals were sacrificed and blood collected for
analysis and treatment in the recovery group lasted for four weeks. In the test groups, the
results of this study on glucose metabolism showed that Diabetes and Atrazine (ATZ)
significantly increased (p<0.05) the fasting blood glucose level and reduced serum estradiol
levels. In conclusion, Atrazine (ATZ) toxicity deranged glucose metabolism but the withdrawal
of Atrazine (ATZ) significantly reversed some of these derangements; with more pronounced
effect following Virgin Coconut Oil (VCO) administration.