Abstract
The article presents the data of 108 patients aged 19 to 59 years old. The role
of the rs752924961 polymorphic variant of the TRP-1 gene and the rs537718989 polymorphic
variant in the TRP-2 gene was assessed. In a molecular genetic study of the tyrosinase -
binding protein (TRP) gene, it was found that the second phase of the excretion of the
TRP1 and TRP2 genes increases the number of carriers of the polymorphism of the
TRP1(0/0) + TRP2(0/0) genes in the second phase of the isolation of the TRP1 and TRP2
genes compared with healthy donors, which may be considered a genetic component of
susceptibility to vitiligo.