Abstract
Abstract: We have studied the results of the distribution of single nucleotide polymorphisms of the inflammatory cytokine genes TNF (G308A), IL2 (T330G), IL6 (C174G) and IL10 (C592A), which are currently common among the population of the Republic of Uzbekistan, involved in the processes of inflammation initiation in individuals with inflammatory diseases. diseases (n=87) and in healthy people without inflammatory diseases (n=71), we conducted a study aimed at studying the characteristics of the distribution. In the studied groups, all genotypic variants of the studied genetic polymorphisms (TNF (G308A), IL2 (T330G), IL6 (C174G), IL10 (C592A)) were analyzed for compliance with the Hardy-Weinberg equilibrium (RHB, p>0.05).
Keywords: chronic suppurative otitis media, allelic polymorphisms of inflammatory cytokine genes, genetic polymorphism