THE ROLE OF MATRIX METALLOPROTEINASES IN THE DEVELOPMENT OF CHRONIC HEART FAILURE

Abstract

the progression of chronic heart failure in patients with myocardial infarction is accompanied by changes in the structure and function of the cardiovascular system. The results of this work made it possible to establish the pattern of participation of MMP-9 and TIMP-4 in the processes accompanying the rearrangement of the extracellular matrix of the heart during postinfarction remodeling of the left ventricle, the development and progression of chronic heart failure.
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