PECULIARITIES OF DYNAMICS OF ZINC AND SELENIUM CONTENT IN BLOOD IN PATIENTS WITH SALMONELOSIS

Abstract

The aim of the study was to study the characteristics of the content of zinc and selenium in serum and blood cells in case of Salmonella infection. The Objective of the study: to identify patterns of relationship with the course of Salmonella infection and the content of selenium and zinc in the blood in patients during the formation of a protracted course of Salmonella infection.
Material and Methods: a neutron-activation method was used to determine the content of selenium and zinc in serum and blood cells in 40 persons of the control group (relatively healthy) and 230 patients with acute salmonellosis with different outcomes of the disease in the dynamics of the disease.
Research results: It was revealed that for the implementation of the immune response in the acute course of Salmonella infection, there is a redistribution of the trace element zinc from the blood serum into the blood corpuscles. In patients with acute salmonellosis with different outcomes of the disease at different periods of the course of the disease, there is a sharp decrease in the content of the microelement selenium in the uniform elements, while the increase in its level in the serum is not so intense, which apparently indicates the use of this microelement to ensure activity in this pathological process of intracellular enzyme systems.