COMPARATIVE RESULTS OF NON-SEGMENT VITILIGO THERAPY WITH PHOTOTHERAPY COMBINED WITH LOCAL APPLICATION OF CREAM CONTAINING COMPLEX OF MICRO ELEMENTS, ANTIOXIDANTS BASED ON GLAUCONITE AND ACTIVATED SILICEOUS WATER

Abstract

Vitiligo is the most frequent pigmentation disorder that strongly affects the quality of life of patients. The prevalence of the disease is 0.5–1% worldwide, although it reaches up to 10% in various ethnic groups and populations [10]. The problem of vitiligo therapy does not lose its relevance, despite the wide variety of proposed methods. In order to stimulate melanogenesis medications such as copper, iron, placenta extract, dopegit, liposomal preparations with antioxidants, silymarin, melaginin, vitamin D, immunosuppressant’s, simvastatin, ginko-biloba, and others were tested both systemically and locally, as well as in combination with physical methods (PUVA, phototherapy, in including infrared radiation, laser therapy), reflexology, oxygen-ozone therapy, PRP therapy, dermabrasion [1,2,3,6,9].