CURRENT PROBLEMS OF MORPHOLOGICAL DIAGNOSIS OF BREAST FIBROADENOMAS IN WOMEN

Abstract

The growth of fibroadenomas is thought to be estrogen-dependent: however, none of the steroid
hormone receptors acting on breast tissue have been shown to cause fibroepithelial damage in the
breast stroma. This article examines estrogen receptor (ER)-α and -β expression in fibroadenomas
and benign, three-borderline, and malignant phyllodes tumors by immunocytochemistry. All of
these scans revealed spindle-shaped cells and one distant metastasis.