EXPRESSION LEVEL OF KI-67 PROLIFERATIVE MARKER IN CELLS OF URINARY BLADDER POLYPS AND PAPILLOMA TISSUES

Abstract

This article presents information on the expression level of proliferative marker
KI-67 in bladder polyp and papilloma tissue cells. Although the proliferative activity of cells
was low only in the basal layer of the covering epithelium of the bladder polyp and
papilloma that we studied, it was confirmed by the brownish expression of the Ki-67
marker in the nuclei of stroma tissue cells. Morphologically, the location of the Ki-67
marker in the nucleus of the lining epithelial cells, in both the nucleus and nucleolus of the
stromal tissue cells, confirms that these cells are in different phases of proliferative and
mitotic activation, i.e. G1, S, G2, M levels.