PROGNOSTIC COURSE OF DISEASE IN PATIENTS WITH DILATED CARDIOMYOPATHY
Keywords:
dilated cardiomyopathy, hypertrophic cardiomyopathy, heart, open arterial passage, prognosis.Abstract
Dilated cardiomyopathy (DCMP) is a severe disease characterized by the
development of cardiomegaly as a result of a decrease in myocardial contractile function,
a primary internal defect of damaged cardiomyocytes, as a result of a strong expansion of
the heart chambers, especially the left ventricle. The disease is characterized by a severe
course, often leading to disability and a high risk of death . In many children, it is difficult
to determine the onset of the disease, because it passes for a long time, almost without
symptoms. In a number of patients, increased weakness, weight gain and/or physical
retardation, fainting, syncopal state, tendency to recurrent pneumonia are noted. Sometimes,
the only sign of the disease is the disturbance of intraventricular and atrioventricular
conduction, changes in extrasystolic appearance on the ECG. Their occurrence is much
lower in children than in adults. About 10 percent of people with dilated cardiomyopathy
are people over age 65. In the United States, the condition is 3 times more common in men
than women and 3 times more common in African Americans than whites. In one year, 5-
8 people out of 100,000 people are affected (10). Despite significant clinical changes in the
course of the disease, its prognosis in children is usually not good .